Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p468 | Other diseases of bone and mineral metabolism | ECTS2016

In vitro model of antioxidant prevention of urolithiasis

Kizivat Tomislav , Smolic Martina , Bilic-Curcic Ines , Smolic Robert , Maric Ivana , Roguljic Hrvoje , Tolusic-Levak Maja , Kuna Lucija , Vcev Aleksandar , Tucak Antun

Urolithiasis is characterized by formation and retention of solid crystals within the urinary tract. There are numerous causes that may lead to urinary stone formation. However, kidney stones are mostly composed of calcium oxalate that predominantly generates free radicals that are toxic to renal tubular cells.The aim of the study is to explore the toxic effect of oxalate to renal epithelial cells and to explore possible effects of antioxidants on its in...